ADME
Outline
Polymorphism analysis data for carefully selected genes is provided by the ADME Core Group. The content of the PharmaADME Core list is combined with VeraCode technology, which uses the golden gate method, to efficiently and rapidly analyze drug metabolism markers.
List of loaded genes
The list includes 184 biomarkers on 34 genes that cover more than 95% of the PharmaADME Core Gene list (http://www.pharmaadme.org/joomla/).
Cytochrome P450
| CYP1A1 | CYP1A2 | CYP2A6 | CYP2B6 | CYP2C19 | CYP2C8 |
| CYP2C9 | CYP2D6 | CYP2E1 | CYP3A4 | CYP3A5 |
Transporter
| ABCB1 | ABCC2 | ABCG2 | SLC15A2 | SLC22A1 | SLC22A2 |
| SLC22A6 | SLCO1B1 | SLCO1B3 | SLCO2B1 | SULT1A1 |
Enzyme
| DRYD | GSTM1 | GSTP1 | GSTT1 | NAT1 | NAT2 |
| TPMT | UGT1A1 | UGT2B15 | UGT2B17 | UGT2B7 | VKORC1 |
Services
Adopting the methods recommended by Illumina, Inc., we return data from polymorphism analyses with high specificity response using primers / probes optimized for the ADME Core gene target region, hybridization response, and high sensitivity detection of marker type with the BeadXpress Reader system.
Click on figure to enlarge
Specific response of target region
